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Impact of Obesity

Obesity Is a Prevalent and Costly Disease1

Obesity has a significant clinical and economic impact because it can be the underlying cause of many comorbidities, such as type 2 diabetes and heart disease.1

Obesity is a chronic disease, not merely a lifestyle issue2

Why is it so hard to lose weight and why does it return? As shown here, there are multiple factors
that may affect weight loss and weight maintenance.

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Science of Obesity

When weight is lost, the body
increases the hunger hormone and
decreases the fullness hormone3

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Genetics

Certain genes may play an important role
in how much weight is gained4,5

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Behavior

Not enough sleep and lack
of physical activity may be
contributing factors6

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Environment

Eating healthy may be challenging
(eg, location, price, time to prepare).
Some individuals have no place to
exercise5,6

All of this information and more in an easy-to-read learning module

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Videos

The Science of Obesity Video

Would you like to learn more about the science of obesity? This video provides a basic scientific understanding of obesity, its potential causes, and potential treatments.

Additional Resources

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50 State Obesity Fact Sheets

Up-to-date information about risks, implications, and productivity data for your state.

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Obesity Conventions Handout

Learn to navigate weight-management and AOM coverage in your organization.

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References: 1. Garvey WT, Mechanick JI, Brett EM, et al; Reviewers of the AACE/ACE Obesity Clinical Practice Guidelines. American Association of Clinical Endocrinologists and American College of Endocrinology comprehensive clinical practice guidelines for medical care of patients with obesity. Endocr Pract. 2016;22(suppl 3):1-203. 2. Recognition of Obesity as a Disease H-440.842. American Medical Association. Accessed May 18, 2023. https://policysearch.ama-assn.org/policyfinder/detail/H-440.842?uri=%2FAMADoc%2FHOD.xml-0-3858.xml 3. Sumithran P, Prendergast LA, Delbridge E, et al. Long-term persistence of hormonal adaptations to weight loss. N Engl J Med. 2011;365(17):1597-1604. 4. Hebebrand J, Hinney A, Knoll N, Volckmar AL, Scherag A. Molecular genetic aspects of weight regulation. Dtsch Arztebl Int. 2013;110(19):338-344. 5. Bray GA, Kim KK, Wilding JPH. Obesity: a chronic relapsing progressive disease process. A position statement of the World Obesity Federation. Obes Rev. 2017;18(7):715-723. 6. Schwartz MW, Seeley RJ, Zeltser LM, et al. Obesity pathogenesis: an Endocrine Society Scientific Statement. Endocr Rev. 2017;38(4):267-296.

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